About Help FAQ

Symbol
Name
ID

Gjc2
gap junction protein, gamma 2
MGI:2153060

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Facial palsy

Abnormality of visual evoked potentials

Lower limb spasticity

Spastic paraparesis

Spastic paraplegia

Upper limb spasticity

Progressive spasticity

Spastic gait

Difficulty walking

CNS hypomyelination

Cerebral hypomyelination

Leukodystrophy

Demyelinating motor neuropathy

Sensory axonal neuropathy

Hypoplasia of the corpus callosum

Cerebral atrophy

Ataxia

Dysmetria

Choreoathetosis

Intention tremor

Head titubation

Babinski sign

Abnormal auditory evoked potentials

Abnormal motor evoked potentials

Abnormality of somatosensory evoked potentials

Decreased motor nerve conduction velocity

Dysarthria

Poor speech

Cognitive impairment

Hyperreflexia

Dystonia

Global developmental delay

Motor delay

Delayed gross motor development

Seizure

Focal impaired awareness seizure

Focal aware seizure

Somatic sensory dysfunction

Distal sensory impairment

Disease(s) Associated with GJC2

hereditary spastic paraplegia 44

hypomyelinating leukodystrophy 2

Mouse Phenotypes

microgliosis

abnormal brain morphology

abnormal brain white matter morphology

abnormal cerebellum white matter morphology

abnormal cerebellum morphology

Purkinje cell degeneration

astrocytosis

increased oligodendrocyte number

neurodegeneration

abnormal oligodendrocyte physiology

abnormal myelination

Availability

Mouse Genotype

Gjc2^tm1(EGFP)Kwi/Gjc2^tm1(EGFP)Kwi

Gjc2^tm2.1Kwi/Gjc2^tm2.1Kwi

Gjc2^tm2.1Kwi/Gjc2⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23